After the death of their supervillain boss, low-level henchpeople Beatrix, Cain, and Harold are once again left jobless, penniless, and squatting in an abandoned grocery store. Unwilling to accept their underling cycle of poverty any longer, Beatrix devises a plan for them to strike out on their own and take over the world by any means necessary. But superheroes, competing baddies, and harsh union rules make the quest for evil success a treacherous journey.