Three lovable astronauts return to Earth after a failed mission to Uranus, and four years of being trapped in a black hole. They land in a deserted New York City, which they continuously explore; until they coincidentally discover other astronauts, who make them aware of the Covid Twenty-Seven virus and it's subsequent pandemic. The newly founded international alliance of astronauts (and the commander's love interest) aim to cross over to Europe, in search of an Italian doctor and his everlasting vaccine; in order to save humanity.